Gastrointestinal Tract

Probiotics for athletes

Probiotic supplementation with variety of Lactobacillus and Bifidobacterium strains showed the improvement of gastrointestinal symptoms during exercise training and competition in athletes. The most beneficial effects to reduce frequency and severity of gut symptoms and improve gut barrier function were demonstrated with multi-strain probiotic consortia. The efficacy increased with duration of probiotic supplementation. For more […]

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Probiotics for the endurance athletes

Our latest intervention study with marathon runners showed that four weeks of supplementation with Lab4 probiotics reduced the incidence and severity of gastrointestinal symptoms prior to and during a marathon race. The runners supplemented with Lab4 probiotics maintained their running speed during the latter stages of the race.

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Probiotics and NAFLD

This review assessed the efficacy of probiotics, prebiotics or synbiotics in the management of non-alcoholic fatty liver disease (NAFLD). A total of 1309 patients with NAFLD from 25 studies (11 probiotic, 9 prebiotic and 7 synbiotic) were included in the meta-analysis. All three treatments combined significantly reduced BMI (-0.37 kg/m2), hepatic alanine aminotransferase (−6.9 U/L), aspartate

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Gut microbiota in nutrition and health

Human gut microbiota plays a key role in disease, nutrition and health. Antibiotics, medications and specific food ingredients influence the composition and diversity of the gut microbiota. Targeting the gut microbiome with probiotics, prebiotics or dietary fibre is beneficial for human health. The analysis of 22 systematic reviews (313 trials, 46 826 participants) showed that

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Upper respiratory symptoms in athletes

Upper tract respiratory symptoms such as sneezing, coughing, sore throat, runny and blocked nose are common among athletes during heavy training and competition. This review focuses on the aetiology of upper respiratory symptoms, mucosal immunity, the role of the gut and airway microbiomes and the use of probiotics and prebiotics to maintain athlete health.  

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The MiBioGen consortium initiative

Recently, the MiBioGen (microbiome genome) consortium initiative was announced with the aim to gain a better understanding of the gut microbiome role as a mediator between genetic predisposition and health or disease in humans. The meta-analysis of human genome-microbiome association studies includes 18 population-level cohorts from countries in Europe, North America and Asia and 18,965

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Gut metabolome and abdominal obesity

The associations of metabolic products derived from gut microbes with age, obesity, host genetics and gut microbiome composition were investigated in the faecal samples of 786 predominantly female twins from the TwinsUK cohort (a national twin registry). The faecal metabolome was largely associated with gut microbial composition (67.7%) and only modestly influenced by host genetics

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Gut microbiome development in neonates

Various factors influence the gut microbiome development in neonates during prenatal, perinatal and postnatal periods, including maternal diet and lifestyle, mode of birth, feeding, antibiotic use and length of gestation. The reciprocal relationship between gut microbiota and gastrointestinal tract development from in utero to postnatal life is discussed in more details.   Link: View the

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