Our Research
Lab4 Probiotics have to date been subject to more than 35 probiotic clinical trials supported by continuous in vitro and in vivo studies. These studies cover a broader range of conditions than any other multi-strain probiotic consortia* in the world, including IBS, immunity, allergy, athletic performance, cognitive function, antibiotics and weight loss.
Lab4 Probiotics Research
More than 100 papers/PhDs published on Lab4 and/or the microbiome
35+
Clinical Trials
10+
PhD Programmes
8+
In Vivo Publications
20+
In Vitro Publications
Research at a Glance
|
Lab4 |
Lab4B |
Lab4P |
Lab4S |
---|---|---|---|---|
Safety Assessment |
|
|
|
|
Gut Health |
|
|
|
|
IBS |
|
|
|
|
Intestinal permeability |
|
|
|
|
Gut symptoms/Bowel habits |
|
|
|
|
Gut microbiota preservation |
|
|
|
|
Antibiotics |
|
|
|
|
Antibiotic prescription |
|
|
|
|
Antibiotic resistance |
|
|
|
|
Allergy |
|
|
|
|
Atopic eczema |
|
|
|
|
Atopic sensitisation |
|
|
|
|
Immune Health |
|
|
|
|
URTI |
|
|
|
|
Immune response |
|
|
|
|
Metabolic Health |
|
|
|
|
Weight management |
|
|
|
|
sdLDL cholesterol |
|
|
|
|
Mental Health |
|
|
|
|
Anxiety, depression in IBS |
|
|
|
|
Anxiety/Cognitive function |
|
|
|
|
Quality of Life |
|
|
|
|
Athletic Performance |
|
|
|
|
Race time |
|
|
|
|
Energy utilisation |
|
|
|
|
Metabolic perturbation |
|
|
|
|
Timeline of Publications
1998
Lab4 Probiotic consortium developed & introduced commercially
1999
First Clinical Trial using Lab4 conducted
2004
The Cambridge Clostridium difficile Study
2005
The Cambridge Probiotic/Antibiotic Trial 1
The Cambridge Probiotic/Antibiotic Trial 2
2008
The Sheffield IBS Trial
2009
The Cardiff Tracking Study
2010
The Swansea ‘Safety in Newborns’
2013
The Cambridge IBS Study
The Adult Immune Response Study
2014
The Swansea Baby Study
The Keele Study
Running to Exhaustion Study
2015
The ProChild Study
2016
The Hertfordshire Study
2017
The Ultra Marathon Endurance Study
2019
The Marathon Endurance Study
2020
The Promagen Study
The Cycling Endurance Study
2021
The Probe Study
The ProChild-2 Study
The Promagen Study: Viral Pandemic Link?
The Marathon Endurance Study: Metabolites
2023
The ProChild-2 Study: Antibiotic Prescriptions
The Probiotics & Healthy Adult Study
2024
The ProChild & ProChild-2 Studies: Preschool children
The IBS in Women Study
Antibiotics and Gut Microbiome Study
For further information on our research, please contact us at info@lab4probiotics.co.uk
*more than two probiotic strains