Probiotic supplementation with variety of Lactobacillus and Bifidobacterium strains showed the improvement of gastrointestinal symptoms during exercise training and competition in athletes. The most beneficial effects to reduce frequency and severity of gut symptoms and improve gut barrier function were demonstrated with multi-strain probiotic consortia. The efficacy increased with duration of probiotic supplementation. For more […]
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Our latest intervention study with marathon runners showed that four weeks of supplementation with Lab4 probiotics reduced the incidence and severity of gastrointestinal symptoms prior to and during a marathon race. The runners supplemented with Lab4 probiotics maintained their running speed during the latter stages of the race.
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This review assessed the efficacy of probiotics, prebiotics or synbiotics in the management of non-alcoholic fatty liver disease (NAFLD). A total of 1309 patients with NAFLD from 25 studies (11 probiotic, 9 prebiotic and 7 synbiotic) were included in the meta-analysis. All three treatments combined significantly reduced BMI (-0.37 kg/m2), hepatic alanine aminotransferase (−6.9 U/L), aspartate
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The age-related changes in the human gut microbiota, potential implications on immune and inflammatory health and targeted therapies for healthy aging are presented in this review. Link: View the Study Nagpal R et al. Gut microbiome and aging: Physiological and mechanistic insights. Nutrition and Healthy Aging 2018; 4: 267-285.
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Upper tract respiratory symptoms such as sneezing, coughing, sore throat, runny and blocked nose are common among athletes during heavy training and competition. This review focuses on the aetiology of upper respiratory symptoms, mucosal immunity, the role of the gut and airway microbiomes and the use of probiotics and prebiotics to maintain athlete health.
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The associations of metabolic products derived from gut microbes with age, obesity, host genetics and gut microbiome composition were investigated in the faecal samples of 786 predominantly female twins from the TwinsUK cohort (a national twin registry). The faecal metabolome was largely associated with gut microbial composition (67.7%) and only modestly influenced by host genetics
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This study investigated the role of gut microbiota in atherosclerosis, a major cause of heart attack and stroke. 316 patients attending vascular prevention clinics in Canada were divided into three distinct phenotypes; (i) 98 patients with much less carotid plaque than predicted by traditional risk factors (Protected), (ii) 138 patients with plaque levels as predicted
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Bidirectional communication between the gut microbiota and brain plays a key role in maintaining brain health. This review focused on the mechanism of this interaction and modulatory role of the gut microbiota in brain-related pathological conditions, such as anxiety, depression, stress, and cognition. In vitro, in vivo, and human studies providing evidence of the microbiota-gut-brain
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The aim of this recent study was to find out whether the probiotic supplementation alongside antibiotic treatment will reduce the incidence of Clostridium difficile infection in adults and children. Individual data of 6851 participants from 18 published randomised controlled trials were included in the statistical analysis. 72.2% of the studies were conducted in adult hospitalised
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A systematic review of 70 studies investigating the use of probiotics in the management of lower gastrointestinal symptoms (IBS, antibiotic-associated diarrhoea, diarrhoea associated with Helicobacter pylori eradication therapy and other conditions) was performed, evidence was graded and recommendations for the physicians provided. Specific probiotics are beneficial in (i) reduction of total symptoms and abdominal pain
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Lab4 by Cultech offers a full range of products and services, from bulk powders to contract manufacturing to individual product manufacture as private label or using our ProVen Biotics brand.
