The Hertfordshire Study
An exploratory investigation of endotoxin levels in novice long distance triathletes, and the effects of a multi-strain probiotic/prebiotic/antioxidant intervention
This study aimed to assess the impact of a multi-strain probiotic/prebiotic/antioxidant intervention on endotoxin levels and gastrointestinal permeability in recreational athletes.
The triathlon athletes taking Lab4 probiotics with prebiotic fibre alone or in combination with antioxidants experienced fewer and less severe exercise-related gut symptoms during their training period.
Reductions in plasma endotoxin levels were observed with Lab4 probiotic/fibre/antioxidant supplementation.
Supplementation of Lab4 probiotics with fibre led to faster race finishing times.
This randomised, double-blind, placebo-controlled study aimed to assess the effect of a 12-week Lab4 probiotic/prebiotic/antioxidant intervention on gut symptoms, endotoxin levels, intestinal permeability and race time in recreational athletes.
- Gut symptom severity scores during training were significantly lower in both Groups 2 and 3 compared to Group 1 (*P<0.001).
- Gut symptoms include bloating, nausea, stomach/intestinal pain or discomfort, cramping, headaches, dizziness, constipation, diarrhoea, belching, urge to urinate & defecate.
- Faster race times were observed with Lab4 probiotics (10.0% reduction, P= 0.058) and Lab4 probiotics plus antioxidants (6.5% reduction) compared to Group 1.
- A significantly faster time was reported for Group 2 during the cycle stage of the triathlon (*P = 0.046).
- Both Group 2 and Group 3 completed the marathon faster than Group 1.
Lab4 probiotics with fibre alone or in combination with antioxidants protect athletes from gut disturbances during endurance training and improve their race finishing times.
Roberts JD et al 2016. An exploratory investigation of endotoxin levels in novice long distance triathletes, and the effects of a multi-strain probiotic/prebiotic/antioxidant intervention.